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Succinylcholine Chloride

CHEMBL983 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
361.3 g/mol
LogP
—
Phase
4

Succinylcholine chloride is a depolarizing neuromuscular blocking agent used for rapid sequence intubation and tracheal intubation as an adjunct to anesthesia, acting as a nicotinic acetylcholine receptor agonist that causes sustained depolarization of the motor end plate, resulting in initial fasciculations followed by flaccid paralysis. Its extremely rapid onset (60 seconds) and short duration (10-15 minutes) due to hydrolysis by plasma cholinesterase make it the agent of choice for emergency intubation. It must be used with great caution in patients with hyperkalemia risk.

Khối lượng phân tử

361,3000 g/mol

TPSA

52,60 Ų

Lĩnh vực điều trị

Infectious Disease Glaucoma Pain Management Rheumatoid Arthritis Schizophrenia Bipolar Disorder Stroke Obesity Major Depressive Disorder Chronic Pain Colorectal Cancer

Cơ chế tác dụng

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C.[Cl-].[Cl-]

                

                

                
                

                    
InChI

                    
InChI=1S/C14H30N2O4.2ClH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

                

                

                

                    
                    

                        
Molecular Formula

                        
C14H30Cl2N2O4

                    

                    
                    

                        
HBD / HBA

                        
- / 6

                    

                    
                    

                        
Liên kết có thể quay

                        
11

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
22

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Succinylcholine chloride is a depolarizing neuromuscular blocking agent used for rapid sequence intubation and tracheal intubation as an adjunct to anesthesia, acting as a nicotinic acetylcholine receptor agonist that causes sustained depolarization of the motor end plate, resulting in initial fasciculations followed by flaccid paralysis. Its extremely rapid onset (60 seconds) and short duration (10-15 minutes) due to hydrolysis by plasma cholinesterase make it the agent of choice for emergency intubation. It must be used with great caution in patients …

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Succinylcholine Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL983.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 22475.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.