Tetradecyl Sulfuric Acid
Tetradecyl sulfuric acid (sodium tetradecyl sulfate, STS) is an anionic detergent sclerosing agent that damages vascular endothelial cells through detergent-mediated disruption of cell membranes, inducing endothelial injury, thrombus formation, and subsequent fibrous obliteration of the treated vessel. It is used for sclerotherapy of varicose veins and spider veins, and for the treatment of venous malformations. The concentration used determines whether small or large vessels are effectively sclerosed.
Peso molecular
294,4500 g/mol
LogP
5,80
TPSA
72,00 Ų
Regla de cinco de Lipinski
Cumple
Mecanismo de acción
Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.
Estructura 2D
Cite this structure
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SMILES
CCCCC(CC)CCC(CC(C)C)OS(=O)(=O)O
InChI
InChI=1S/C14H30O4S/c1-5-7-8-13(6-2)9-10-14(11-12(3)4)18-19(15,16)17/h12-14H,5-11H2,1-4H3,(H,15,16,17)
Molecular Formula
C14H30O4S
HBD / HBA
1 / 4
Enlaces Rotables
14
Átomos Pesados
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
Tetradecyl sulfuric acid (sodium tetradecyl sulfate, STS) is an anionic detergent sclerosing agent that damages vascular endothelial cells through detergent-mediated disruption of cell membranes, inducing endothelial injury, thrombus formation, and subsequent fibrous obliteration of the treated vessel. It is used for sclerotherapy of varicose veins and spider veins, and for the treatment of venous malformations. The concentration used determines whether small or large vessels are effectively sclerosed.
Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.
Yes, Tetradecyl Sulfuric Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201345. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5248. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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