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Tetradecyl Sulfuric Acid

CHEMBL1201345 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
294.4 g/mol
LogP
5.8
Phase
4

Tetradecyl sulfuric acid (sodium tetradecyl sulfate, STS) is an anionic detergent sclerosing agent that damages vascular endothelial cells through detergent-mediated disruption of cell membranes, inducing endothelial injury, thrombus formation, and subsequent fibrous obliteration of the treated vessel. It is used for sclerotherapy of varicose veins and spider veins, and for the treatment of venous malformations. The concentration used determines whether small or large vessels are effectively sclerosed.

Khối lượng phân tử

294,4500 g/mol

LogP

5,80

TPSA

72,00 Ų

Lipinski RO5

Đạt

Cơ chế tác dụng

Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.

Cấu trúc 2D

SVG PNG

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SMILES

                    
CCCCC(CC)CCC(CC(C)C)OS(=O)(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C14H30O4S/c1-5-7-8-13(6-2)9-10-14(11-12(3)4)18-19(15,16)17/h12-14H,5-11H2,1-4H3,(H,15,16,17)

                

                

                

                    
                    

                        
Molecular Formula

                        
C14H30O4S

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
Liên kết có thể quay

                        
14

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Tetradecyl sulfuric acid (sodium tetradecyl sulfate, STS) is an anionic detergent sclerosing agent that damages vascular endothelial cells through detergent-mediated disruption of cell membranes, inducing endothelial injury, thrombus formation, and subsequent fibrous obliteration of the treated vessel. It is used for sclerotherapy of varicose veins and spider veins, and for the treatment of venous malformations. The concentration used determines whether small or large vessels are effectively sclerosed.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Tetradecyl Sulfuric Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201345.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5248.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.