Tetradecyl Sulfuric Acid
Tetradecyl sulfuric acid (sodium tetradecyl sulfate, STS) is an anionic detergent sclerosing agent that damages vascular endothelial cells through detergent-mediated disruption of cell membranes, inducing endothelial injury, thrombus formation, and subsequent fibrous obliteration of the treated vessel. It is used for sclerotherapy of varicose veins and spider veins, and for the treatment of venous malformations. The concentration used determines whether small or large vessels are effectively sclerosed.
分子量
294.4500 g/mol
LogP
5.80
TPSA
72.00 Ų
リピンスキーの五則
適合
作用機序
Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.
2D構造
Cite this structure
Embed this structure
SMILES
CCCCC(CC)CCC(CC(C)C)OS(=O)(=O)O
InChI
InChI=1S/C14H30O4S/c1-5-7-8-13(6-2)9-10-14(11-12(3)4)18-19(15,16)17/h12-14H,5-11H2,1-4H3,(H,15,16,17)
Molecular Formula
C14H30O4S
HBD / HBA
1 / 4
回転可能結合数
14
重原子数
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Tetradecyl sulfuric acid (sodium tetradecyl sulfate, STS) is an anionic detergent sclerosing agent that damages vascular endothelial cells through detergent-mediated disruption of cell membranes, inducing endothelial injury, thrombus formation, and subsequent fibrous obliteration of the treated vessel. It is used for sclerotherapy of varicose veins and spider veins, and for the treatment of venous malformations. The concentration used determines whether small or large vessels are effectively sclerosed.
Causes endothelial damage and inflammation when injected into a vessel, leading to thrombosis, fibrosis, and eventual obliteration of the treated vein or vascular malformation.
Yes, Tetradecyl Sulfuric Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201345. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5248. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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