Chlordiazepoxide Hydrochloride

CHEMBL1200703 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

336.2 g/mol

LogP

—

Phase

4

The hydrochloride salt form of chlordiazepoxide is the standard oral and injectable preparation used for anxiety and alcohol withdrawal management. It shares the same benzodiazepine pharmacology as the parent compound. Risk of respiratory depression increases when combined with other CNS depressants such as opioids or alcohol.

Masse moléculaire

336,2000 g/mol

TPSA

48,20 Å²

Aires thérapeutiques

Major Depressive Disorder

Mécanisme d'action

Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, …

Structure 2D

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SMILES

CNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=[N+]([O-])C1.Cl

InChI

InChI=1S/C16H14ClN3O.ClH/c1-18-15-10-20(21)16(11-5-3-2-4-6-11)13-9-12(17)7-8-14(13)19-15;/h2-9H,10H2,1H3,(H,18,19);1H

Molecular Formula

C16H15Cl2N3O

HBD / HBA

2 / 3

Liaisons Rotatives

1

Atomes Lourds

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

The hydrochloride salt form of chlordiazepoxide is the standard oral and injectable preparation used for anxiety and alcohol withdrawal management. It shares the same benzodiazepine pharmacology as the parent compound. Risk of respiratory depression increases when combined with other CNS depressants such as opioids or alcohol.

Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.

Yes, Chlordiazepoxide Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200703. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9916. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C16H15Cl2N3O
Synonymes: 4

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.