Chlordiazepoxide Hydrochloride

CHEMBL1200703 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

336.2 g/mol

LogP

—

Phase

4

The hydrochloride salt form of chlordiazepoxide is the standard oral and injectable preparation used for anxiety and alcohol withdrawal management. It shares the same benzodiazepine pharmacology as the parent compound. Risk of respiratory depression increases when combined with other CNS depressants such as opioids or alcohol.

Moleküler Ağırlık

336,2000 g/mol

TPSA

48,20 Å²

Terapötik Alanlar

Major Depressive Disorder

Etki Mekanizması

Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanizma

Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, …

2D Yapı

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SMILES

CNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=[N+]([O-])C1.Cl

InChI

InChI=1S/C16H14ClN3O.ClH/c1-18-15-10-20(21)16(11-5-3-2-4-6-11)13-9-12(17)7-8-14(13)19-15;/h2-9H,10H2,1H3,(H,18,19);1H

Molecular Formula

C16H15Cl2N3O

HBD / HBA

2 / 3

Döndürülebilir Bağlar

1

Ağır Atomlar

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

The hydrochloride salt form of chlordiazepoxide is the standard oral and injectable preparation used for anxiety and alcohol withdrawal management. It shares the same benzodiazepine pharmacology as the parent compound. Risk of respiratory depression increases when combined with other CNS depressants such as opioids or alcohol.

Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.

Yes, Chlordiazepoxide Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200703. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9916. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Hızlı Veriler

Formül: C16H15Cl2N3O
Eş Anlamlılar: 4

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.