Sotalol

CHEMBL471 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

272.4 g/mol

LogP

0.2

Phase

4

This dual-action medication both blocks beta-adrenergic receptors and stabilizes the heart's electrical rhythm by extending the action potential, making it useful for treating atrial fibrillation and serious ventricular arrhythmias. Because it can itself cause dangerous heart rhythm abnormalities in some patients, initial dosing is typically monitored in hospital.

Masse moléculaire

272,3700 g/mol

LogP

0,20

TPSA

86,80 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Cardiovascular Disease Stroke Hypertension Heart Failure Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

Cite this structure

Embed this structure

SMILES

CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1

InChI

InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3

Molecular Formula

C12H20N2O3S

HBD / HBA

3 / 5

Liaisons Rotatives

6

Atomes Lourds

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This dual-action medication both blocks beta-adrenergic receptors and stabilizes the heart's electrical rhythm by extending the action potential, making it useful for treating atrial fibrillation and serious ventricular arrhythmias. Because it can itself cause dangerous heart rhythm abnormalities in some patients, initial dosing is typically monitored in hospital.

Yes, Sotalol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL471. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5253. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

Vous cherchez des informations accessibles aux patients ?

Sotalol sur PillFYI

Structure

Données Clés

Formule: C12H20N2O3S
Synonymes: 4

Liens externes

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.