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Sotalol

CHEMBL471 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
272.4 g/mol
LogP
0.2
Phase
4

This dual-action medication both blocks beta-adrenergic receptors and stabilizes the heart's electrical rhythm by extending the action potential, making it useful for treating atrial fibrillation and serious ventricular arrhythmias. Because it can itself cause dangerous heart rhythm abnormalities in some patients, initial dosing is typically monitored in hospital.

Khối lượng phân tử

272,3700 g/mol

LogP

0,20

TPSA

86,80 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Cardiovascular Disease Stroke Hypertension Heart Failure Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

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SMILES

                    
CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H20N2O3S

                    

                    
                    

                        
HBD / HBA

                        
3 / 5

                    

                    
                    

                        
Liên kết có thể quay

                        
6

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
18

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This dual-action medication both blocks beta-adrenergic receptors and stabilizes the heart's electrical rhythm by extending the action potential, making it useful for treating atrial fibrillation and serious ventricular arrhythmias. Because it can itself cause dangerous heart rhythm abnormalities in some patients, initial dosing is typically monitored in hospital.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sotalol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL471.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5253.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.