Sotalol

CHEMBL471 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

272.4 g/mol

LogP

0.2

Phase

4

This dual-action medication both blocks beta-adrenergic receptors and stabilizes the heart's electrical rhythm by extending the action potential, making it useful for treating atrial fibrillation and serious ventricular arrhythmias. Because it can itself cause dangerous heart rhythm abnormalities in some patients, initial dosing is typically monitored in hospital.

Moleküler Ağırlık

272,3700 g/mol

LogP

0,20

TPSA

86,80 Å²

Lipinski RO5

Geçer

Terapötik Alanlar

Cardiovascular Disease Stroke Hypertension Heart Failure Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

Cite this structure

Embed this structure

SMILES

CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1

InChI

InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3

Molecular Formula

C12H20N2O3S

HBD / HBA

3 / 5

Döndürülebilir Bağlar

6

Ağır Atomlar

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

This dual-action medication both blocks beta-adrenergic receptors and stabilizes the heart's electrical rhythm by extending the action potential, making it useful for treating atrial fibrillation and serious ventricular arrhythmias. Because it can itself cause dangerous heart rhythm abnormalities in some patients, initial dosing is typically monitored in hospital.

Yes, Sotalol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL471. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5253. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Hızlı Veriler

Formül: C12H20N2O3S
Eş Anlamlılar: 4

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Tıbbi Sorumluluk Reddi

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.