Thiotepa

CHEMBL671 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

189.2 g/mol

LogP

0.5

Phase

4

This chemotherapy drug is used to treat certain cancers including bladder cancer, breast cancer, and ovarian cancer, and is also used in high doses to prepare patients for bone marrow transplantation. It works by attaching chemical groups to DNA strands in cancer cells, preventing them from dividing. It can be given intravenously or directly into the bladder.

Masse moléculaire

189,2200 g/mol

LogP

0,50

TPSA

41,10 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Ovarian Cancer Bladder Cancer Rheumatoid Arthritis Chronic Obstructive Pulmonary Disease Multiple Sclerosis Lymphoma Hypertension Breast Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

S=P(N1CC1)(N1CC1)N1CC1

InChI

InChI=1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2

Molecular Formula

C6H12N3PS

HBD / HBA

- / 4

Liaisons Rotatives

3

Atomes Lourds

11

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This chemotherapy drug is used to treat certain cancers including bladder cancer, breast cancer, and ovarian cancer, and is also used in high doses to prepare patients for bone marrow transplantation. It works by attaching chemical groups to DNA strands in cancer cells, preventing them from dividing. It can be given intravenously or directly into the bladder.

Yes, Thiotepa is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL671. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5453. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C6H12N3PS
Synonymes: 2

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.