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Thiotepa

CHEMBL671 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
189.2 g/mol
LogP
0.5
Phase
4

This chemotherapy drug is used to treat certain cancers including bladder cancer, breast cancer, and ovarian cancer, and is also used in high doses to prepare patients for bone marrow transplantation. It works by attaching chemical groups to DNA strands in cancer cells, preventing them from dividing. It can be given intravenously or directly into the bladder.

분자량

189.2200 g/mol

LogP

0.50

TPSA

41.10 Ų

리핀스키 5의 법칙

통과

치료 영역

Ovarian Cancer Bladder Cancer Rheumatoid Arthritis Chronic Obstructive Pulmonary Disease Multiple Sclerosis Lymphoma Hypertension Breast Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
S=P(N1CC1)(N1CC1)N1CC1

                

                

                
                

                    
InChI

                    
InChI=1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C6H12N3PS

                    

                    
                    

                        
HBD / HBA

                        
- / 4

                    

                    
                    

                        
회전 가능 결합

                        
3

                    

                    
                    
                    

                        
무거운 원자

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
This chemotherapy drug is used to treat certain cancers including bladder cancer, breast cancer, and ovarian cancer, and is also used in high doses to prepare patients for bone marrow transplantation. It works by attaching chemical groups to DNA strands in cancer cells, preventing them from dividing. It can be given intravenously or directly into the bladder.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Thiotepa is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL671.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5453.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.