Vigabatrin

CHEMBL89598 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

129.2 g/mol

LogP

-2.2

Phase

4

This anticonvulsant medication is used to treat infantile spasms (a severe form of epilepsy in babies) and as an add-on treatment for complex partial seizures that have not responded to other medications. It works by blocking an enzyme that breaks down GABA, increasing levels of this inhibitory neurotransmitter in the brain. A serious and irreversible side effect is progressive narrowing of peripheral vision (visual field loss), which can occur in up to one-third of patients.

Masse moléculaire

129,1600 g/mol

LogP

-2,20

TPSA

63,30 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Glaucoma Epilepsy Non-Alcoholic Fatty Liver Disease Obesity Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

C=CC(N)CCC(=O)O

InChI

InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)

Molecular Formula

C6H11NO2

HBD / HBA

2 / 3

Liaisons Rotatives

4

Atomes Lourds

9

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This anticonvulsant medication is used to treat infantile spasms (a severe form of epilepsy in babies) and as an add-on treatment for complex partial seizures that have not responded to other medications. It works by blocking an enzyme that breaks down GABA, increasing levels of this inhibitory neurotransmitter in the brain. A serious and irreversible side effect is progressive narrowing of peripheral vision (visual field loss), which can occur in up to one-third of patients.

Yes, Vigabatrin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL89598. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5665. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C6H11NO2
Synonymes: 5

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.