Antagonist
A substance that binds to a receptor without activating it, blocking the action of endogenous ligands or agonists. Competitive antagonists can be overcome by increased agonist; irreversible antagonists cannot.
Exemples
- Naloxone (opioid antagonist)
- Propranolol (beta-blocker)
- Losartan (AT1 antagonist)
Le saviez-vous ?
A substance that binds to a receptor without activating it, blocking the action of endogenous ligands or agonists. Competitive antagonists can be overcome by increased agonist; irreversible antagonists cannot.