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Ipragliflozin

CHEMBL2018096 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
404.5 g/mol
LogP
2.5
Phase
4

This SGLT2 inhibitor works by blocking a kidney protein that reabsorbs glucose, causing excess sugar to be excreted in the urine and thereby lowering blood sugar levels in people with type 2 diabetes. It also promotes modest weight loss and blood pressure reduction.

आणविक भार

404.5000 g/mol

LogP

2.50

TPSA

118.00 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

Non-Alcoholic Fatty Liver Disease Type 2 Diabetes

क्रिया का तंत्र

Selectively inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule, reducing glucose reabsorption and promoting urinary glucose excretion. This lowers blood glucose levels independently of insulin secretion.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Selectively inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule, reducing glucose reabsorption and promoting urinary glucose excretion. This lowers blood glucose levels independently of insulin secretion.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
OC[C@H]1O[C@@H](c2ccc(F)c(Cc3cc4ccccc4s3)c2)[C@H](O)[C@@H](O)[C@@H]1O

                

                

                
                

                    
InChI

                    
InChI=1S/C21H21FO5S/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-21,23-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C21H21FO5S

                    

                    
                    

                        
HBD / HBA

                        
4 / 7

                    

                    
                    

                        
घूर्णनीय बंधन

                        
4

                    

                    
                    
                    

                        
भारी परमाणु

                        
28

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
This SGLT2 inhibitor works by blocking a kidney protein that reabsorbs glucose, causing excess sugar to be excreted in the urine and thereby lowering blood sugar levels in people with type 2 diabetes. It also promotes modest weight loss and blood pressure reduction.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Selectively inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubule, reducing glucose reabsorption and promoting urinary glucose excretion. This lowers blood glucose levels independently of insulin secretion.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Ipragliflozin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2018096.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 10453870.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.