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Selectivity

Pharmacodynamics

The ability of a drug to preferentially act on a specific receptor subtype, tissue, or organ. Higher selectivity generally means fewer off-target effects. Expressed as the ratio of binding affinities.

उदाहरण

  • Beta-1 selective: metoprolol, atenolol
  • COX-2 selective: celecoxib
  • SSRI selectivity for SERT

क्या आप जानते हैं?

The ability of a drug to preferentially act on a specific receptor subtype, tissue, or organ. Higher selectivity generally means fewer off-target effects. Expressed as the ratio of binding affinities.