Selectivity
The ability of a drug to preferentially act on a specific receptor subtype, tissue, or organ. Higher selectivity generally means fewer off-target effects. Expressed as the ratio of binding affinities.
Examples
- Beta-1 selective: metoprolol, atenolol
- COX-2 selective: celecoxib
- SSRI selectivity for SERT
Did You Know?
The ability of a drug to preferentially act on a specific receptor subtype, tissue, or organ. Higher selectivity generally means fewer off-target effects. Expressed as the ratio of binding affinities.