Potassium Nitrate

CHEMBL1644029 Phase 4 Disetujui Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
101.1 g/mol
LogP
Phase
4

Potassium nitrate is an inorganic salt that can act as a nitrate donor, being metabolized to nitrite and subsequently to nitric oxide, which causes vasodilation of blood vessels through activation of soluble guanylate cyclase and smooth muscle relaxation. It has been used historically as an antihypertensive and antianginal agent, and topically in desensitizing toothpastes for dentinal hypersensitivity through occlusion of dentinal tubules.

Berat Molekul

101,1030 g/mol

TPSA

62,90 Ų

Area Terapeutik

Mekanisme Kerja

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Struktur 2D

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SMILES

O=[N+]([O-])[O-].[K+]

InChI

InChI=1S/K.NO3/c;2-1(3)4/q+1;-1

Molecular Formula

KNO3

HBD / HBA

- / 3

Ikatan yang Dapat Dirotasi

0

Atom Berat

5

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

Potassium nitrate is an inorganic salt that can act as a nitrate donor, being metabolized to nitrite and subsequently to nitric oxide, which causes vasodilation of blood vessels through activation of soluble guanylate cyclase and smooth muscle relaxation. It has been used historically as an antihypertensive and antianginal agent, and topically in desensitizing toothpastes for dentinal hypersensitivity through occlusion of dentinal tubules.

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Yes, Potassium Nitrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1644029. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 24434. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.