Potassium Nitrate
Potassium nitrate is an inorganic salt that can act as a nitrate donor, being metabolized to nitrite and subsequently to nitric oxide, which causes vasodilation of blood vessels through activation of soluble guanylate cyclase and smooth muscle relaxation. It has been used historically as an antihypertensive and antianginal agent, and topically in desensitizing toothpastes for dentinal hypersensitivity through occlusion of dentinal tubules.
Moleküler Ağırlık
101,1030 g/mol
TPSA
62,90 Ų
Terapötik Alanlar
Etki Mekanizması
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
2D Yapı
Cite this structure
Embed this structure
SMILES
O=[N+]([O-])[O-].[K+]
InChI
InChI=1S/K.NO3/c;2-1(3)4/q+1;-1
Molecular Formula
KNO3
HBD / HBA
- / 3
Döndürülebilir Bağlar
0
Ağır Atomlar
5
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
Potassium nitrate is an inorganic salt that can act as a nitrate donor, being metabolized to nitrite and subsequently to nitric oxide, which causes vasodilation of blood vessels through activation of soluble guanylate cyclase and smooth muscle relaxation. It has been used historically as an antihypertensive and antianginal agent, and topically in desensitizing toothpastes for dentinal hypersensitivity through occlusion of dentinal tubules.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Potassium Nitrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1644029. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 24434. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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