Sodium Thiosulfate
Sodium thiosulfate is used as an antidote for cyanide poisoning (in combination with sodium nitrite or hydroxocobalamin) by acting as a sulfur donor that allows rhodanese enzyme to convert cyanide to the less toxic thiocyanate for renal excretion. It is also used to treat cisplatin-induced nephrotoxicity and ototoxicity by chelating platinum compounds, and topically for tinea versicolor and calciphylaxis. Its reactive sulfhydryl groups provide reductive detoxification of multiple cytotoxic agents.
Berat Molekul
158,1100 g/mol
TPSA
104,00 Ų
Area Terapeutik
Mekanisme Kerja
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Struktur 2D
Cite this structure
Embed this structure
SMILES
O.O.O.O.O.O=S([O-])([O-])=S.[Na+].[Na+]
InChI
InChI=1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2
Molecular Formula
Na2O3S2
HBD / HBA
- / 4
Ikatan yang Dapat Dirotasi
0
Atom Berat
7
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
Sodium thiosulfate is used as an antidote for cyanide poisoning (in combination with sodium nitrite or hydroxocobalamin) by acting as a sulfur donor that allows rhodanese enzyme to convert cyanide to the less toxic thiocyanate for renal excretion. It is also used to treat cisplatin-induced nephrotoxicity and ototoxicity by chelating platinum compounds, and topically for tinea versicolor and calciphylaxis. Its reactive sulfhydryl groups provide reductive detoxification of multiple cytotoxic agents.
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Yes, Sodium Thiosulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2096650. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 24477. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="sodium-thiosulfate"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/sodium-thiosulfate/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/sodium-thiosulfate/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/sodium-thiosulfate/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="sodium-thiosulfate"></drugfyi-drug>