PTGS2 (Cyclooxygenase-2)
PTGS2
Inducible cyclooxygenase isoform upregulated during inflammation and pain signaling.
Fungsi
Catalyzes prostaglandin H2 synthesis at sites of inflammation. Primary target of NSAIDs and selective COX-2 inhibitors (coxibs).
Obat yang Bekerja pada Target Ini
| Obat | Aksi | Utama |
|---|---|---|
| Celecoxib | Inhibitor | Ya |
| Ibuprofen | Inhibitor | Ya |
| Naproxen | Inhibitor | Ya |
| Acetaminophen | Inhibitor | Ya |
| Aspirin | Inhibitor | — |