SLC6A4 (Serotonin Transporter)
SLC6A4
Sodium-dependent serotonin transporter responsible for reuptake of 5-HT from the synaptic cleft.
Fungsi
Primary target for SSRIs and SNRIs. Inhibition increases synaptic serotonin.
Obat yang Bekerja pada Target Ini
| Obat | Aksi | Utama |
|---|---|---|
| Duloxetine | Inhibitor | Ya |
| Escitalopram | Inhibitor | Ya |
| Fluoxetine | Inhibitor | Ya |
| Sertraline | Inhibitor | Ya |
| Venlafaxine | Inhibitor | Ya |
| Trazodone | Inhibitor | — |
| Tramadol | Inhibitor | — |