Brincidofovir

CHEMBL203321 Phase 4 承認済み Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

561.7 g/mol

LogP

4.9

Phase

4

An oral antiviral medication used for the treatment of human smallpox disease caused by variola virus. It is a lipid conjugate of cidofovir that improves oral bioavailability while reducing kidney toxicity associated with cidofovir itself. It is considered a medical countermeasure for bioterrorism-related smallpox exposure.

分子量

561.7000 g/mol

LogP

4.90

TPSA

144.00 Å²

リピンスキーの五則

適合

治療領域

Lymphoma

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

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SMILES

CCCCCCCCCCCCCCCCOCCCOP(=O)(O)CO[C@H](CO)Cn1ccc(N)nc1=O

InChI

InChI=1S/C27H52N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-35-20-16-21-37-38(33,34)24-36-25(23-31)22-30-18-17-26(28)29-27(30)32/h17-18,25,31H,2-16,19-24H2,1H3,(H,33,34)(H2,28,29,32)/t25-/m0/s1

Molecular Formula

C27H52N3O7P

HBD / HBA

3 / 7

回転可能結合数

26

重原子数

38

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

An oral antiviral medication used for the treatment of human smallpox disease caused by variola virus. It is a lipid conjugate of cidofovir that improves oral bioavailability while reducing kidney toxicity associated with cidofovir itself. It is considered a medical countermeasure for bioterrorism-related smallpox exposure.

Yes, Brincidofovir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL203321. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 483477. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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構造

クイックデータ

分子式: C27H52N3O7P
同義語: 1

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医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.