Brincidofovir
An oral antiviral medication used for the treatment of human smallpox disease caused by variola virus. It is a lipid conjugate of cidofovir that improves oral bioavailability while reducing kidney toxicity associated with cidofovir itself. It is considered a medical countermeasure for bioterrorism-related smallpox exposure.
Peso Molecular
561,7000 g/mol
LogP
4,90
TPSA
144,00 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CCCCCCCCCCCCCCCCOCCCOP(=O)(O)CO[C@H](CO)Cn1ccc(N)nc1=O
InChI
InChI=1S/C27H52N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-35-20-16-21-37-38(33,34)24-36-25(23-31)22-30-18-17-26(28)29-27(30)32/h17-18,25,31H,2-16,19-24H2,1H3,(H,33,34)(H2,28,29,32)/t25-/m0/s1
Molecular Formula
C27H52N3O7P
HBD / HBA
3 / 7
Ligações Rotacionáveis
26
Átomos Pesados
38
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
An oral antiviral medication used for the treatment of human smallpox disease caused by variola virus. It is a lipid conjugate of cidofovir that improves oral bioavailability while reducing kidney toxicity associated with cidofovir itself. It is considered a medical countermeasure for bioterrorism-related smallpox exposure.
Yes, Brincidofovir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL203321. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 483477. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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