Candesartan
An angiotensin II receptor blocker used to treat high blood pressure and heart failure. By blocking the angiotensin II receptor, it dilates blood vessels and reduces the workload on the heart. It is also used to protect kidney function in patients with type 2 diabetes and high blood pressure.
分子量
610.6640 g/mol
LogP
4.10
TPSA
119.00 Ų
リピンスキーの五則
適合
治療領域
薬物分類
作用機序
Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.
2D構造
Cite this structure
Embed this structure
SMILES
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O
InChI
InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
Molecular Formula
C33H34N6O6
HBD / HBA
2 / 7
回転可能結合数
7
重原子数
33
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
An angiotensin II receptor blocker used to treat high blood pressure and heart failure. By blocking the angiotensin II receptor, it dilates blood vessels and reduces the workload on the heart. It is also used to protect kidney function in patients with type 2 diabetes and high blood pressure.
Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.
Key pharmacokinetic parameters for Candesartan: Half-life: 9 hours.
Yes, Candesartan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
References & Data Sources
- PubChem — National Center for Biotechnology Information (NCBI). CID 2541. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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