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Candesartan

Phase 4 Đã phê duyệt Small molecule
Half-Life
9 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
610.7 g/mol
LogP
4.1
Phase
4

An angiotensin II receptor blocker used to treat high blood pressure and heart failure. By blocking the angiotensin II receptor, it dilates blood vessels and reduces the workload on the heart. It is also used to protect kidney function in patients with type 2 diabetes and high blood pressure.

Khối lượng phân tử

610,6640 g/mol

LogP

4,10

TPSA

119,00 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Ovarian Cancer Cardiovascular Disease Rheumatoid Arthritis Migraine Bipolar Disorder Chronic Kidney Disease Stroke Hyperlipidemia Obesity Type 2 Diabetes Hypertension Breast Cancer Hepatitis C Heart Failure Atrial Fibrillation

Phân loại thuốc

C — C - Cardiovascular System

Cơ chế tác dụng

Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

Pharmacokinetics (PK)

Half-Life 9 hours

Pharmacodynamics (PD)

Cơ chế

Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)

                

                

                

                    
                    

                        
Molecular Formula

                        
C33H34N6O6

                    

                    
                    

                        
HBD / HBA

                        
2 / 7

                    

                    
                    

                        
Liên kết có thể quay

                        
7

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
33

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
An angiotensin II receptor blocker used to treat high blood pressure and heart failure. By blocking the angiotensin II receptor, it dilates blood vessels and reduces the workload on the heart. It is also used to protect kidney function in patients with type 2 diabetes and high blood pressure.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Candesartan: Half-life: 9 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Candesartan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Atorvastatin
                            Small molecule
                        
                        
                        
                            Amlodipine
                            Small molecule
                        
                        
                        
                            Lisinopril
                            Small molecule
                        
                        
                        
                            Metoprolol
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2541.
                Chemical information database.
            
        
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Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.