Chloroprocaine Hydrochloride

CHEMBL944 Phase 4 承認済み Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
307.2 g/mol
LogP
Phase
4

The hydrochloride salt formulation of chloroprocaine is the clinical preparation used for epidural and infiltration anesthesia. It shares the rapid onset and short duration of action of the parent compound due to fast ester hydrolysis. It is favored in labor analgesia and ambulatory surgical settings.

分子量

307.2100 g/mol

TPSA

55.60 Ų

治療領域

作用機序

Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.

2D構造

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SMILES

CCN(CC)CCOC(=O)c1ccc(N)cc1Cl.Cl

InChI

InChI=1S/C13H19ClN2O2.ClH/c1-3-16(4-2)7-8-18-13(17)11-6-5-10(15)9-12(11)14;/h5-6,9H,3-4,7-8,15H2,1-2H3;1H

Molecular Formula

C13H20Cl2N2O2

HBD / HBA

2 / 4

回転可能結合数

7

重原子数

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

The hydrochloride salt formulation of chloroprocaine is the clinical preparation used for epidural and infiltration anesthesia. It shares the rapid onset and short duration of action of the parent compound due to fast ester hydrolysis. It is favored in labor analgesia and ambulatory surgical settings.

Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.

Yes, Chloroprocaine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL944. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 441348. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.