Triprolidine Hydrochloride

CHEMBL3188034 Phase 4 承認済み Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
314.9 g/mol
LogP
Phase
4

Triprolidine hydrochloride is the hydrochloride salt of triprolidine, a pyrrolidine-class first-generation H1 antihistamine used for relief of allergic rhinitis, urticaria, and cold symptoms. It blocks histamine at peripheral and central H1 receptors, producing antiallergic and sedative effects. This salt form is widely used in combination cold and allergy preparations.

分子量

314.9000 g/mol

TPSA

16.10 Ų

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

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SMILES

Cc1ccc(/C(=C\CN2CCCC2)c2ccccn2)cc1.Cl.O

InChI

InChI=1S/C19H22N2.ClH.H2O/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;;/h2-3,6-12H,4-5,13-15H2,1H3;1H;1H2/b18-11+;;

Molecular Formula

C19H23ClN2

HBD / HBA

1 / 2

回転可能結合数

4

重原子数

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

Triprolidine hydrochloride is the hydrochloride salt of triprolidine, a pyrrolidine-class first-generation H1 antihistamine used for relief of allergic rhinitis, urticaria, and cold symptoms. It blocks histamine at peripheral and central H1 receptors, producing antiallergic and sedative effects. This salt form is widely used in combination cold and allergy preparations.

Yes, Triprolidine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3188034. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5702129. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.