Dexfenfluramine
The dextro-isomer of fenfluramine, an appetite suppressant that increases serotonin levels in the brain and was used for short-term weight management in obesity. It was withdrawn from the market in 1997 due to serious risks of heart valve damage and primary pulmonary hypertension. It is no longer available.
분자량
231.2600 g/mol
LogP
3.40
TPSA
12.00 Ų
리핀스키 5의 법칙
통과
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D 구조
Cite this structure
Embed this structure
SMILES
CCN[C@@H](C)Cc1cccc(C(F)(F)F)c1
InChI
InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1
Molecular Formula
C12H16F3N
HBD / HBA
1 / 4
회전 가능 결합
4
무거운 원자
16
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
자주 묻는 질문
The dextro-isomer of fenfluramine, an appetite suppressant that increases serotonin levels in the brain and was used for short-term weight management in obesity. It was withdrawn from the market in 1997 due to serious risks of heart valve damage and primary pulmonary hypertension. It is no longer available.
Yes, Dexfenfluramine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL248702. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 66265. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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