Mitotane
This medication damages the outer layer of the adrenal gland, reducing the production of steroid hormones and directly killing adrenal cancer cells. It is used to treat adrenal cortex cancer and to control excess hormone production from adrenal tumors.
분자량
320.0000 g/mol
LogP
6.20
TPSA
0.00 Ų
리핀스키 5의 법칙
통과
치료 영역
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D 구조
Cite this structure
Embed this structure
SMILES
Clc1ccc(C(c2ccccc2Cl)C(Cl)Cl)cc1
InChI
InChI=1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
Molecular Formula
C14H10Cl4
HBD / HBA
- / -
회전 가능 결합
3
무거운 원자
18
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
자주 묻는 질문
This medication damages the outer layer of the adrenal gland, reducing the production of steroid hormones and directly killing adrenal cancer cells. It is used to treat adrenal cortex cancer and to control excess hormone production from adrenal tumors.
Yes, Mitotane is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1670. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4211. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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