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Mitotane

CHEMBL1670 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
320.0 g/mol
LogP
6.2
Phase
4

This medication damages the outer layer of the adrenal gland, reducing the production of steroid hormones and directly killing adrenal cancer cells. It is used to treat adrenal cortex cancer and to control excess hormone production from adrenal tumors.

Khối lượng phân tử

320,0000 g/mol

LogP

6,20

TPSA

0,00 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Bladder Cancer Prostate Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

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SMILES

                    
Clc1ccc(C(c2ccccc2Cl)C(Cl)Cl)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H

                

                

                

                    
                    

                        
Molecular Formula

                        
C14H10Cl4

                    

                    
                    

                        
HBD / HBA

                        
- / -

                    

                    
                    

                        
Liên kết có thể quay

                        
3

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
18

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This medication damages the outer layer of the adrenal gland, reducing the production of steroid hormones and directly killing adrenal cancer cells. It is used to treat adrenal cortex cancer and to control excess hormone production from adrenal tumors.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Mitotane is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1670.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4211.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.