Mitotane

CHEMBL1670 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

320.0 g/mol

LogP

6.2

Phase

4

This medication damages the outer layer of the adrenal gland, reducing the production of steroid hormones and directly killing adrenal cancer cells. It is used to treat adrenal cortex cancer and to control excess hormone production from adrenal tumors.

分子量

320.0000 g/mol

LogP

6.20

TPSA

0.00 Å²

Lipinski 五规则

符合

治疗领域

Bladder Cancer Prostate Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

Clc1ccc(C(c2ccccc2Cl)C(Cl)Cl)cc1

InChI

InChI=1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H

Molecular Formula

C14H10Cl4

HBD / HBA

- / -

可旋转键数

3

重原子数

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

This medication damages the outer layer of the adrenal gland, reducing the production of steroid hormones and directly killing adrenal cancer cells. It is used to treat adrenal cortex cancer and to control excess hormone production from adrenal tumors.

Yes, Mitotane is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1670. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4211. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C14H10Cl4
同义词: 1

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.