Pentolinium
A ganglionic blocking agent formerly used to treat severe hypertension by blocking both sympathetic and parasympathetic ganglia, causing vasodilation and a reduction in blood pressure. It is no longer in clinical use due to its unpredictable effects and the availability of safer antihypertensives.
분자량
240.4300 g/mol
LogP
2.40
TPSA
0.00 Ų
리핀스키 5의 법칙
통과
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D 구조
Cite this structure
Embed this structure
SMILES
C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1
InChI
InChI=1S/C15H32N2/c1-16(12-6-7-13-16)10-4-3-5-11-17(2)14-8-9-15-17/h3-15H2,1-2H3/q+2
Molecular Formula
C15H32N2+2
HBD / HBA
- / -
회전 가능 결합
6
무거운 원자
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
자주 묻는 질문
A ganglionic blocking agent formerly used to treat severe hypertension by blocking both sympathetic and parasympathetic ganglia, causing vasodilation and a reduction in blood pressure. It is no longer in clinical use due to its unpredictable effects and the availability of safer antihypertensives.
Yes, Pentolinium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1271. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5850. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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