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Sulfur

CHEMBL1235452 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
32.1 g/mol
LogP
0.5
Phase
4

Sulfur is an elemental non-metal with keratolytic, antifungal, and antibacterial properties, used topically for treatment of acne, seborrheic dermatitis, rosacea, scabies, and psoriasis. Its mechanism involves formation of hydrogen sulfide and pentathionic acid by skin surface bacteria, which are directly toxic to Sarcoptes scabiei mites and bacteria, and keratolytic activity that reduces comedone formation. It is one of the oldest medicinal substances and remains in use in over-the-counter topical formulations.

분자량

32.0700 g/mol

LogP

0.50

TPSA

1.00 Ų

리핀스키 5의 법칙

통과

치료 영역

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Endometriosis Benign Prostatic Hyperplasia Glaucoma Cardiovascular Disease Respiratory Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Infectious Disease Melanoma Gastroesophageal Reflux Disease Inflammatory Bowel Disease Systemic Lupus Erythematosus Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Hyperlipidemia Obesity Lymphoma Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Gout Chronic Pain Malaria HIV/AIDS Hepatitis C Tuberculosis Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

작용 기전

Promotes the shedding of the outer layer of skin (stratum corneum) by disrupting intercellular adhesion between keratinocytes. This softens and removes thickened, scaly, or hyperkeratotic skin.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

기전

Promotes the shedding of the outer layer of skin (stratum corneum) by disrupting intercellular adhesion between keratinocytes. This softens and removes thickened, scaly, or hyperkeratotic skin.

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
S1SSSSSSS1

                

                

                
                

                    
InChI

                    
InChI=1S/S8/c1-2-4-6-8-7-5-3-1

                

                

                

                    
                    

                        
Molecular Formula

                        
S

                    

                    
                    

                        
HBD / HBA

                        
- / 1

                    

                    
                    

                        
회전 가능 결합

                        
0

                    

                    
                    
                    

                        
무거운 원자

                        
1

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
Sulfur is an elemental non-metal with keratolytic, antifungal, and antibacterial properties, used topically for treatment of acne, seborrheic dermatitis, rosacea, scabies, and psoriasis. Its mechanism involves formation of hydrogen sulfide and pentathionic acid by skin surface bacteria, which are directly toxic to Sarcoptes scabiei mites and bacteria, and keratolytic activity that reduces comedone formation. It is one of the oldest medicinal substances and remains in use in over-the-counter topical formulations.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Promotes the shedding of the outer layer of skin (stratum corneum) by disrupting intercellular adhesion between keratinocytes. This softens and removes thickened, scaly, or hyperkeratotic skin.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Sulfur is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1235452.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5362487.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.