Torsemide
This loop diuretic medication helps the kidneys remove excess fluid and salt from the body, and is used to treat fluid retention (edema) caused by heart failure, kidney disease, or liver cirrhosis, as well as high blood pressure. It acts on the kidney's loop of Henle to block sodium reabsorption, producing a strong diuretic effect. Potassium levels should be monitored as the medication can cause potassium loss.
분자량
348.4000 g/mol
LogP
2.70
TPSA
109.00 Ų
리핀스키 5의 법칙
통과
치료 영역
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D 구조
Cite this structure
Embed this structure
SMILES
Cc1cccc(Nc2ccncc2S(=O)(=O)NC(=O)NC(C)C)c1
InChI
InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)
Molecular Formula
C16H20N4O3S
HBD / HBA
3 / 5
회전 가능 결합
5
무거운 원자
24
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
자주 묻는 질문
This loop diuretic medication helps the kidneys remove excess fluid and salt from the body, and is used to treat fluid retention (edema) caused by heart failure, kidney disease, or liver cirrhosis, as well as high blood pressure. It acts on the kidney's loop of Henle to block sodium reabsorption, producing a strong diuretic effect. Potassium levels should be monitored as the medication can cause potassium loss.
Yes, Torsemide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1148. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 41781. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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