Torsemide

CHEMBL1148 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

348.4 g/mol

LogP

2.7

Phase

4

This loop diuretic medication helps the kidneys remove excess fluid and salt from the body, and is used to treat fluid retention (edema) caused by heart failure, kidney disease, or liver cirrhosis, as well as high blood pressure. It acts on the kidney's loop of Henle to block sodium reabsorption, producing a strong diuretic effect. Potassium levels should be monitored as the medication can cause potassium loss.

分子量

348.4000 g/mol

LogP

2.70

TPSA

109.00 Å²

Lipinski 五规则

符合

治疗领域

Cardiovascular Disease Chronic Kidney Disease Hypertension Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

Cite this structure

Embed this structure

SMILES

Cc1cccc(Nc2ccncc2S(=O)(=O)NC(=O)NC(C)C)c1

InChI

InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)

Molecular Formula

C16H20N4O3S

HBD / HBA

3 / 5

可旋转键数

5

重原子数

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

This loop diuretic medication helps the kidneys remove excess fluid and salt from the body, and is used to treat fluid retention (edema) caused by heart failure, kidney disease, or liver cirrhosis, as well as high blood pressure. It acts on the kidney's loop of Henle to block sodium reabsorption, producing a strong diuretic effect. Potassium levels should be monitored as the medication can cause potassium loss.

Yes, Torsemide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1148. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 41781. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

正在寻找患者友好型信息？

Torsemide 在 PillFYI 上

结构

快速数据

分子式: C16H20N4O3S
同义词: 3

外部链接

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.