Alprostadil

CHEMBL495 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

354.5 g/mol

LogP

3.2

Phase

4

A synthetic form of prostaglandin E1 that relaxes smooth muscle in blood vessels and is used to treat erectile dysfunction by increasing blood flow to the penis, and also to keep the ductus arteriosus open in newborns with certain congenital heart defects until surgery can be performed. It can be administered by penile injection, urethral suppository, or intravenously depending on the condition being treated.

Peso Molecular

354,5000 g/mol

LogP

3,20

TPSA

94,80 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Cardiovascular Disease Age-Related Macular Degeneration Pain Management Rheumatoid Arthritis Parkinson's Disease Epilepsy Migraine Generalized Anxiety Disorder Insomnia Gastroesophageal Reflux Disease Inflammatory Bowel Disease Psoriasis Systemic Lupus Erythematosus Multiple Sclerosis Non-Alcoholic Fatty Liver Disease Stroke Deep Vein Thrombosis / Pulmonary Embolism Obesity Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Chronic Pain HIV/AIDS Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O

InChI

InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

Molecular Formula

C20H34O5

HBD / HBA

3 / 5

Ligações Rotacionáveis

13

Átomos Pesados

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A synthetic form of prostaglandin E1 that relaxes smooth muscle in blood vessels and is used to treat erectile dysfunction by increasing blood flow to the penis, and also to keep the ductus arteriosus open in newborns with certain congenital heart defects until surgery can be performed. It can be administered by penile injection, urethral suppository, or intravenously depending on the condition being treated.

Yes, Alprostadil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL495. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5280723. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Alprostadil no PillFYI

Estrutura

Dados Rápidos

Fórmula: C20H34O5
Sinônimos: 4

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.