Apraclonidine Hydrochloride

CHEMBL1200379 Phase 4 Aprovado Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
281.6 g/mol
LogP
Phase
4

The hydrochloride salt of apraclonidine, an ophthalmic agent that lowers eye pressure by activating alpha-2 receptors to decrease fluid production inside the eye. It is used in the short-term management of glaucoma and after certain eye procedures.

Peso Molecular

281,6000 g/mol

TPSA

62,40 Ų

Áreas Terapêuticas

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

Cl.Nc1cc(Cl)c(N=C2NCCN2)c(Cl)c1

InChI

InChI=1S/C9H10Cl2N4.ClH/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9;/h3-4H,1-2,12H2,(H2,13,14,15);1H

Molecular Formula

C9H11Cl3N4

HBD / HBA

4 / 2

Ligações Rotacionáveis

2

Átomos Pesados

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

The hydrochloride salt of apraclonidine, an ophthalmic agent that lowers eye pressure by activating alpha-2 receptors to decrease fluid production inside the eye. It is used in the short-term management of glaucoma and after certain eye procedures.

Yes, Apraclonidine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200379. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 51763. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.