Atropine
A muscarinic receptor antagonist derived from the belladonna plant that blocks the effects of acetylcholine on the parasympathetic nervous system, increasing heart rate, drying secretions, and relaxing smooth muscle. It is used in emergencies for bradycardia and to reverse certain poisonings.
Peso Molecular
289,4000 g/mol
LogP
1,80
TPSA
49,80 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Mecanismo de Ação
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2
InChI
InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
Molecular Formula
C17H23NO3
HBD / HBA
1 / 4
Ligações Rotacionáveis
5
Átomos Pesados
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A muscarinic receptor antagonist derived from the belladonna plant that blocks the effects of acetylcholine on the parasympathetic nervous system, increasing heart rate, drying secretions, and relaxing smooth muscle. It is used in emergencies for bradycardia and to reverse certain poisonings.
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Yes, Atropine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL517712. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 174174. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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