Cefadroxil
A first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis and is used to treat infections caused by susceptible organisms, including streptococcal pharyngitis and skin infections. It has a long half-life that allows for once or twice daily dosing. Hypersensitivity reactions, including anaphylaxis, can occur especially in patients allergic to penicillins.
Peso Molecular
363,4000 g/mol
LogP
-2,10
TPSA
158,00 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Mecanismo de Ação
Disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting the final transpeptidation step of peptidoglycan synthesis. The resulting cell wall defects cause osmotic instability and bacteriolysis.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting the final transpeptidation step of peptidoglycan synthesis. The resulting cell wall defects cause osmotic instability and bacteriolysis.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccc(O)cc3)[C@H]2SC1
InChI
InChI=1S/C16H17N3O5S/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24)/t10-,11-,15-/m1/s1
Molecular Formula
C16H17N3O5S
HBD / HBA
4 / 7
Ligações Rotacionáveis
4
Átomos Pesados
25
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis and is used to treat infections caused by susceptible organisms, including streptococcal pharyngitis and skin infections. It has a long half-life that allows for once or twice daily dosing. Hypersensitivity reactions, including anaphylaxis, can occur especially in patients allergic to penicillins.
Disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting the final transpeptidation step of peptidoglycan synthesis. The resulting cell wall defects cause osmotic instability and bacteriolysis.
Yes, Cefadroxil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1644. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 47965. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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