Diclofenac Sodium
The sodium salt and most common oral formulation of diclofenac, an NSAID used for chronic inflammatory conditions including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Extended-release tablets allow twice-daily dosing.
Peso Molecular
318,1000 g/mol
TPSA
52,20 Ų
Áreas Terapêuticas
Mecanismo de Ação
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
O=C([O-])Cc1ccccc1Nc1c(Cl)cccc1Cl.[Na+]
InChI
InChI=1S/C14H11Cl2NO2.Na/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1
Molecular Formula
C14H10Cl2NNaO2
HBD / HBA
1 / 3
Ligações Rotacionáveis
4
Átomos Pesados
20
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
The sodium salt and most common oral formulation of diclofenac, an NSAID used for chronic inflammatory conditions including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Extended-release tablets allow twice-daily dosing.
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Yes, Diclofenac Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1034. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5018304. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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