Doxepin

CHEMBL1628227 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

279.4 g/mol

LogP

4.3

Phase

4

A tricyclic antidepressant also used in low doses to treat insomnia. It works by affecting multiple neurotransmitter systems including serotonin, norepinephrine, and histamine.

Peso Molecular

279,4000 g/mol

LogP

4,30

TPSA

12,50 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Pain Management Parkinson's Disease Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Lymphoma Breast Cancer Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

CN(C)CCC=C1c2ccccc2COc2ccccc21

InChI

InChI=1S/C19H21NO/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19/h3-6,8-12H,7,13-14H2,1-2H3

Molecular Formula

C19H21NO

HBD / HBA

- / 2

Ligações Rotacionáveis

3

Átomos Pesados

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A tricyclic antidepressant also used in low doses to treat insomnia. It works by affecting multiple neurotransmitter systems including serotonin, norepinephrine, and histamine.

Yes, Doxepin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1628227. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3158. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

Procura informações acessíveis para o paciente?

Doxepin no PillFYI

Estrutura

Dados Rápidos

Fórmula: C19H21NO
Sinônimos: 4

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.