Enalapril Maleate
The maleate salt form of enalapril, this blood pressure medication relaxes blood vessels by blocking the enzyme that produces the vessel-constricting hormone angiotensin II. The maleate salt form is the standard oral formulation.
Peso Molecular
492,5000 g/mol
TPSA
171,00 Ų
Áreas Terapêuticas
Mecanismo de Ação
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O.O=C(O)/C=C\C(=O)O
InChI
InChI=1S/C20H28N2O5.C4H4O4/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25;5-3(6)1-2-4(7)8/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,16-,17-;/m0./s1
Molecular Formula
C24H32N2O9
HBD / HBA
4 / 10
Ligações Rotacionáveis
12
Átomos Pesados
35
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
The maleate salt form of enalapril, this blood pressure medication relaxes blood vessels by blocking the enzyme that produces the vessel-constricting hormone angiotensin II. The maleate salt form is the standard oral formulation.
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
Yes, Enalapril Maleate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200659. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5388961. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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