💊 Thuốc A-Z 🧬 Đích tác dụng 🛠 Công cụ 📚 Hướng dẫn
Tất cả thuốc Phân loại thuốc Lĩnh vực điều trị Tác dụng phụ
Hướng dẫn Từ điển thuật ngữ Dòng thời gian
So sánh Hành trình của thuốc Các họ thuốc
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย

Enalapril Maleate

CHEMBL1200659 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
492.5 g/mol
LogP
—
Phase
4

The maleate salt form of enalapril, this blood pressure medication relaxes blood vessels by blocking the enzyme that produces the vessel-constricting hormone angiotensin II. The maleate salt form is the standard oral formulation.

Khối lượng phân tử

492,5000 g/mol

TPSA

171,00 Ų

Lĩnh vực điều trị

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Melanoma Systemic Lupus Erythematosus Chronic Kidney Disease Stroke Hyperlipidemia Obesity Lymphoma Type 2 Diabetes Hypertension Breast Cancer Chronic Pain Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

Cơ chế tác dụng

Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O.O=C(O)/C=C\C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C20H28N2O5.C4H4O4/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25;5-3(6)1-2-4(7)8/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,16-,17-;/m0./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H32N2O9

                    

                    
                    

                        
HBD / HBA

                        
4 / 10

                    

                    
                    

                        
Liên kết có thể quay

                        
12

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
35

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
The maleate salt form of enalapril, this blood pressure medication relaxes blood vessels by blocking the enzyme that produces the vessel-constricting hormone angiotensin II. The maleate salt form is the standard oral formulation.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Enalapril Maleate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200659.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5388961.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.