Hydroxychloroquine Sulfate

CHEMBL1690 Phase 4 Aprovado Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
434.0 g/mol
LogP
Phase
4

This is the sulfate salt form of hydroxychloroquine, an antimalarial and immunomodulatory drug used to treat lupus, rheumatoid arthritis, and certain other inflammatory conditions. It works by reducing immune system overactivity and has also been studied experimentally for various other conditions. Periodic eye monitoring is necessary with long-term treatment.

Peso Molecular

434,0000 g/mol

TPSA

131,00 Ų

Áreas Terapêuticas

Mecanismo de Ação

Accumulates in lysosomes raising pH; inhibits toll-like receptor signaling.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Accumulates in lysosomes raising pH; inhibits toll-like receptor signaling.

Estrutura 2D

SVG PNG

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SMILES

CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12.O=S(=O)(O)O

InChI

InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

Molecular Formula

C18H28ClN3O5S

HBD / HBA

4 / 8

Ligações Rotacionáveis

9

Átomos Pesados

28

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

This is the sulfate salt form of hydroxychloroquine, an antimalarial and immunomodulatory drug used to treat lupus, rheumatoid arthritis, and certain other inflammatory conditions. It works by reducing immune system overactivity and has also been studied experimentally for various other conditions. Periodic eye monitoring is necessary with long-term treatment.

Accumulates in lysosomes raising pH; inhibits toll-like receptor signaling.

Yes, Hydroxychloroquine Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1690. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 12947. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.