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Ibuprofen Lysine

CHEMBL1201141 Phase 4 Aprovado Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
352.5 g/mol
LogP
—
Phase
4

This is the lysine salt form of ibuprofen, which may dissolve more quickly than standard ibuprofen, potentially providing faster onset of pain relief. The lysine conjugate improves the solubility of ibuprofen for certain formulations, including intravenous use for closing patent ductus arteriosus in premature infants. It shares the anti-inflammatory, analgesic, and antipyretic properties of ibuprofen.

Peso Molecular

352,5000 g/mol

TPSA

127,00 Ų

Áreas Terapêuticas

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Benign Prostatic Hyperplasia Glaucoma Cardiovascular Disease Respiratory Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Generalized Anxiety Disorder Insomnia Infectious Disease Melanoma Gastroesophageal Reflux Disease Inflammatory Bowel Disease Obstetrics & Gynecology Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Urology Stroke Hyperlipidemia Obesity Lymphoma Gastroenterology Hypertension Major Depressive Disorder Breast Cancer Chronic Pain Malaria Tuberculosis Prostate Cancer Colorectal Cancer Leukemia

Mecanismo de Ação

Non-selective COX inhibitor reducing prostaglandin synthesis.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Non-selective COX inhibitor reducing prostaglandin synthesis.

Estrutura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC(C)Cc1ccc(C(C)C(=O)O)cc1.NCCCC[C@H](N)C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C13H18O2.C6H14N2O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;7-4-2-1-3-5(8)6(9)10/h4-7,9-10H,8H2,1-3H3,(H,14,15);5H,1-4,7-8H2,(H,9,10)/t;5-/m.0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H32N2O4

                    

                    
                    

                        
HBD / HBA

                        
4 / 6

                    

                    
                    

                        
Ligações Rotacionáveis

                        
9

                    

                    
                    
                    

                        
Átomos Pesados

                        
25

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Perguntas frequentes

                

                    
                    

                        
                        

                            
This is the lysine salt form of ibuprofen, which may dissolve more quickly than standard ibuprofen, potentially providing faster onset of pain relief. The lysine conjugate improves the solubility of ibuprofen for certain formulations, including intravenous use for closing patent ductus arteriosus in premature infants. It shares the anti-inflammatory, analgesic, and antipyretic properties of ibuprofen.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Non-selective COX inhibitor reducing prostaglandin synthesis.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Ibuprofen Lysine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201141.
                Open-access bioactivity database.
            
        
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                PubChem — National Center for Biotechnology Information (NCBI).
                CID 9841440.
                Chemical information database.
            
        
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Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Aviso Médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.