Ibutilide

CHEMBL533 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

384.6 g/mol

LogP

4.0

Phase

4

This antiarrhythmic drug is used to rapidly convert atrial fibrillation or atrial flutter to normal sinus rhythm. It works primarily by prolonging cardiac action potentials through effects on potassium and sodium ion channels. It is given by intravenous infusion in a monitored setting due to the risk of potentially life-threatening ventricular arrhythmias.

Peso Molecular

384,6000 g/mol

LogP

4,00

TPSA

78,00 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1

InChI

InChI=1S/C20H36N2O3S/c1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25/h12-15,20-21,23H,4-11,16-17H2,1-3H3

Molecular Formula

C20H36N2O3S

HBD / HBA

2 / 5

Ligações Rotacionáveis

14

Átomos Pesados

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

This antiarrhythmic drug is used to rapidly convert atrial fibrillation or atrial flutter to normal sinus rhythm. It works primarily by prolonging cardiac action potentials through effects on potassium and sodium ion channels. It is given by intravenous infusion in a monitored setting due to the risk of potentially life-threatening ventricular arrhythmias.

Yes, Ibutilide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL533. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 60753. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Ibutilide no PillFYI

Estrutura

Dados Rápidos

Fórmula: C20H36N2O3S
Sinônimos: 1

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.