Lamivudine
An antiretroviral nucleoside reverse transcriptase inhibitor used to treat HIV infection and chronic hepatitis B. It works by blocking the reverse transcriptase enzyme that HIV needs to replicate.
Peso Molecular
229,2600 g/mol
LogP
-0,90
TPSA
113,00 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Mecanismo de Ação
Inhibits viral reverse transcriptase, blocking the conversion of viral RNA to DNA and preventing viral replication in infected host cells.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits viral reverse transcriptase, blocking the conversion of viral RNA to DNA and preventing viral replication in infected host cells.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1
InChI
InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1
Molecular Formula
C8H11N3O3S
HBD / HBA
2 / 4
Ligações Rotacionáveis
2
Átomos Pesados
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
An antiretroviral nucleoside reverse transcriptase inhibitor used to treat HIV infection and chronic hepatitis B. It works by blocking the reverse transcriptase enzyme that HIV needs to replicate.
Inhibits viral reverse transcriptase, blocking the conversion of viral RNA to DNA and preventing viral replication in infected host cells.
Yes, Lamivudine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL141. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 60825. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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