Suloctidil

CHEMBL404849 Phase 4 Aprovado Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
337.6 g/mol
LogP
5.8
Phase
4

Suloctidil is a vasoactive compound with calcium channel blocking and anti-platelet aggregation properties, used historically in some countries for the treatment of peripheral and cerebral vascular insufficiency and claudication. It reduces vascular smooth muscle tone and inhibits platelet function, improving blood flow in atherosclerotic vessels. It has been withdrawn from many markets due to hepatotoxicity concerns.

Peso Molecular

337,6000 g/mol

LogP

5,80

TPSA

57,60 Ų

Regra dos 5 de Lipinski

Aprovado

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

CCCCCCCCNC(C)C(O)c1ccc(SC(C)C)cc1

InChI

InChI=1S/C20H35NOS/c1-5-6-7-8-9-10-15-21-17(4)20(22)18-11-13-19(14-12-18)23-16(2)3/h11-14,16-17,20-22H,5-10,15H2,1-4H3

Molecular Formula

C20H35NOS

HBD / HBA

2 / 3

Ligações Rotacionáveis

12

Átomos Pesados

23

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

Suloctidil is a vasoactive compound with calcium channel blocking and anti-platelet aggregation properties, used historically in some countries for the treatment of peripheral and cerebral vascular insufficiency and claudication. It reduces vascular smooth muscle tone and inhibits platelet function, improving blood flow in atherosclerotic vessels. It has been withdrawn from many markets due to hepatotoxicity concerns.

Yes, Suloctidil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL404849. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 6604413. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.