Suvorexant

CHEMBL1083659 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

450.9 g/mol

LogP

4.9

Phase

4

Rather than sedating the brain broadly, this medication blocks orexin receptors — the wake-promoting signaling system — to allow natural sleep to occur without forcing sedation. It is used for insomnia in adults and is also being studied for its potential to improve sleep quality in patients with Alzheimer's disease.

Peso Molecular

450,9000 g/mol

LogP

4,90

TPSA

80,30 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Bipolar Disorder Generalized Anxiety Disorder Insomnia Multiple Sclerosis Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

Cite this structure

Embed this structure

SMILES

Cc1ccc(-n2nccn2)c(C(=O)N2CCN(c3nc4cc(Cl)ccc4o3)CC[C@H]2C)c1

InChI

InChI=1S/C23H23ClN6O2/c1-15-3-5-20(30-25-8-9-26-30)18(13-15)22(31)29-12-11-28(10-7-16(29)2)23-27-19-14-17(24)4-6-21(19)32-23/h3-6,8-9,13-14,16H,7,10-12H2,1-2H3/t16-/m1/s1

Molecular Formula

C23H23ClN6O2

HBD / HBA

- / 6

Ligações Rotacionáveis

3

Átomos Pesados

32

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

Rather than sedating the brain broadly, this medication blocks orexin receptors — the wake-promoting signaling system — to allow natural sleep to occur without forcing sedation. It is used for insomnia in adults and is also being studied for its potential to improve sleep quality in patients with Alzheimer's disease.

Yes, Suvorexant is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1083659. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 24965990. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

Procura informações acessíveis para o paciente?

Suvorexant no PillFYI

Estrutura

Dados Rápidos

Fórmula: C23H23ClN6O2
Sinônimos: 1

Links Externos

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.