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Trimethoprim Sulfate

CHEMBL2110367 Phase 4 Aprovado Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
678.7 g/mol
LogP
—
Phase
4

A sulfate salt form of trimethoprim with the same therapeutic properties. This antibiotic is used to treat and prevent urinary tract infections and is often combined with sulfamethoxazole (as co-trimoxazole or Bactrim) to treat a broader range of infections including certain types of pneumonia.

Peso Molecular

678,7000 g/mol

TPSA

294,00 Ų

Áreas Terapêuticas

Glaucoma Lymphoma Leukemia

Mecanismo de Ação

Dihydrofolate reductase inhibitor (bacterial selective).

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Dihydrofolate reductase inhibitor (bacterial selective).

Estrutura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC.COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC.O=S(=O)(O)O

                

                

                
                

                    
InChI

                    
InChI=1S/2C14H18N4O3.H2O4S/c2*1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-5(2,3)4/h2*5-7H,4H2,1-3H3,(H4,15,16,17,18);(H2,1,2,3,4)

                

                

                

                    
                    

                        
Molecular Formula

                        
C28H38N8O10S

                    

                    
                    

                        
HBD / HBA

                        
6 / 18

                    

                    
                    

                        
Ligações Rotacionáveis

                        
10

                    

                    
                    
                    

                        
Átomos Pesados

                        
47

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Perguntas frequentes

                

                    
                    

                        
                        

                            
A sulfate salt form of trimethoprim with the same therapeutic properties. This antibiotic is used to treat and prevent urinary tract infections and is often combined with sulfamethoxazole (as co-trimoxazole or Bactrim) to treat a broader range of infections including certain types of pneumonia.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Dihydrofolate reductase inhibitor (bacterial selective).

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Trimethoprim Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2110367.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 64936.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Aviso Médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.